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Fat Molecule Ceramide May Factor in Muscle Loss in Older Adults

Research Suggests Interference with Muscle Response to Resistance Exercise

BOSTON–As men and women age, increasing quantities of fat tissue inevitably take up residence in skeletal muscle. A small study of older and younger men conducted at the Jean Mayer USDA Human Nutrition Research Center on Aging (USDA HNRCA) at Tufts University suggests that a build-up of a fat molecule known as ceramide might play a leading role in muscle deterioration in older adults. The results of the study were published online this month by the Journal of Applied Physiology, a publication of the American Physiological Society.


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